| Natalie du Toit | Para-swimming | 13 | 2 | 0 | 15 | Paralympian 2004, 2008, 2012 |
| Fanie Lombaard | Para-athletics | 6 | 2 | 1 | 9 | Paralympian 1996, 2000, 2004, 2008 |
| Oscar Pistorius | Para-athletics | 6 | 1 | 1 | 8 | Paralympian 2004, 2008, 2012 |
| Ernst van Dyk | Para-athletics, Para-cycling | 2 | 3 | 3 | 8 | Paralympian 1992, 1996, 2000, 2004, 2008, 2012, 2016, 2020 |
| Scott Field | Para-swimming | 0 | 5 | 2 | 7 | Paralympian 2000, 2004 |
| Hilton Langenhoven | Para-athletics | 4 | 3 | 0 | 7 | Paralympian 2004, 2008, 2012, 2016 |
| Malcolm Pringle | Para-athletics | 3 | 3 | 1 | 7 | Paralympian 1996, 2000, 2004 |
| Ilse Hayes | Para-athletics | 2 | 3 | 1 | 6 | Paralympian 2004, 2008, 2012, 2016 |
| Tadgh Slattery | Para-swimming | 2 | 3 | 1 | 6 | Paralympian 1992, 1996, 2004, 2008, 2012 |
| Dyan Buis | Para-athletics | 1 | 2 | 2 | 5 | Paralympian 2012, 2016, 2020 |
| Charl Bouwer | Para-swimming | 2 | 2 | 0 | 4 | Paralympian 2004, 2008, 2012 |
| Craig Groenewald | Para-swimming | 0 | 0 | 4 | 4 | Paralympian 1996, 2000 |
| Philippa Johnson | Para-equestrian Dessage | 2 | 2 | 0 | 4 | Paralympian 2004, 2008, 2012, 2016, 2020, 2024 |
| Ebert Kleynhans | Para-swimming | 3 | 1 | 0 | 4 | Paralympian 1996, 2000, 2004 |
| Michael Louwrens | Para-athletics | 3 | 0 | 1 | 4 | Paralympian 1996, 2000, 2004, 2008, 2012 |
| Tebogo Mokgalagadi | Para-athletics | 2 | 1 | 1 | 4 | Paralympian 2004, 2008, 2012 |
| Zanele Situ | Para-athletics | 2 | 1 | 1 | 4 | Paralympian 2000, 2004, 2008, 2012, 2016, 2020 |
| Fanie van der Merwe | Para-athletics | 3 | 0 | 1 | 4 | Paralympian 2008, 2012, 2016 |
| Anrune Weyers (Liebenberg) | Para-athletics | 1 | 2 | 1 | 4 | Paralympian 2012, 2016, 2020 |
| Christelle Bosker | Para-athletics | 2 | 0 | 1 | 3 | Paralympian 2000 |
| Steyn Humphries | Para-athletics | 1 | 1 | 1 | 3 | Paralympian 1996 |
| Ntando Mahlangu | Para-athletics | 2 | 1 | 0 | 3 | Paralympian 2016, 2020 |
| Mpumelelo Mhlongo | Para-athletics | 2 | 0 | 1 | 3 | Paralympian 2016, 2020, 2024 |
| Kevin Paul | Para-swimming | 2 | 1 | 0 | 3 | Paralympian 2012, 2016, 2020 |
| Pieter Badenhorst | Para-athletics | 1 | 1 | 0 | 2 | Paralympian 1992, 1996, 2000 |
| Louzanne Coetzee | Para-athletics | 0 | 1 | 2 | 3 | Paralympian 2016, 2020, 2024 |
| Charl du Toit | Para-athletics | 2 | 0 | 0 | 2 | Paralympian 2012, 2016, 2020 |
| Arnu Fourie | Para-athletics | 1 | 0 | 1 | 2 | Paralympian 2008, 2012, 2016 |
| Jacobus Jonker | Para-athletics | 0 | 2 | 0 | 2 | Paralympian 1996, 2000 |
| Leon Labuschagne | Para-athletics | 2 | 0 | 0 | 2 | Paralympian 1992, 1996 |
| Stefanus Lombaard | Para-athletics | 2 | 0 | 0 | 2 | Paralympian 1996 |
| Neil Louw | Para-athletics | 0 | 0 | 2 | 2 | Paralympian 1992, 1996 |
| Nathan Meyer | Para-athletics | 2 | 0 | 0 | 2 | Paralympian 2000, 2004 |
| Riaan Nel | Para-cycling | 0 | 1 | 1 | 2 | Paralympian 2000, 2004, 2008 |
| Nicholas Newman | Para-athletics | 1 | 0 | 1 | 2 | Paralympian 2004, 2008 |
| Jonathan Ntutu | Para-athletics | 0 | 1 | 1 | 2 | Paralympian 2004, 2008, 2012, 2016, 2020 |
| David Roos | Para-athletics | 0 | 1 | 1 | 2 | Paralympian 2000, 2004, 2008, 2012 |
| Shireen Sapiro | Para-swimming | 1 | 0 | 1 | 2 | Paralympian 2004, 2008, 2012 |
| Tanya Swanepoel | Para-athletics | 0 | 1 | 1 | 2 | Paralympian 1996, 2000 |
| Jean-Jacques Terblanche | Para-swimming | 1 | 0 | 1 | 2 | Paralympian 1996 |
| Jaco Janse van Vuuren | Para-athletics | 0 | 1 | 1 | 2 | Paralympian 1996, 2000 |
| Gert van der Merwe | Para-athletics | 2 | 0 | 0 | 2 | Paralympian 1996, 2000 |
| Hannes Venter | Para-swimming | 0 | 1 | 1 | 2 | Paralympian 2000 |
| Deidre Buller | Para-bowls | 1 | 0 | 0 | 1 | Paralympian 1996 |
| Pieter du Preez | Para-athletics, para-cycling | 1 | 0 | 1 | 2 | Paralympian 2016, 2020, 2024 |
| Moekie Grobbelaar | Powerlifting | 0 | 0 | 1 | 1 | Paralympian 2000, 2004, 2008 |
| Reinhardt Hamman | Para-athletics | 1 | 0 | 0 | 1 | Paralympian 2016, 2020 |
| Margaret Harriman | Para-bowls | 0 | 0 | 1 | 1 | Paralympian 1996 |
| Achmat Hassiem | Para-swimming | 0 | 0 | 1 | 1 | Paralympian 2008, 2012 |
| Hendri Herbst | Para-swimming | 0 | 0 | 1 | 1 | Paralympian 2012, 2016 |
| Derrick Hyman | Para-athletics | 1 | 0 | 0 | 1 | Paralympian 1992 |
| Sheryl James | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 2020, 2024 |
| Gavin Kilpatrick | Para-cycling | 0 | 0 | 1 | 1 | Paralympian 2008 |
| Simone Kruger | Para-cycling | 1 | 0 | 0 | 1 | Paralympian 2020, 2024 |
| Riaan Liebenberg | Para-athletics | 0 | 1 | 0 | 1 | Paralympian 2000 |
| Stephanus Lombaard | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 1996 |
| Daniel Louw | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 1996 |
| Marius Louw | Para-cycling | 0 | 0 | 1 | 1 | Paralympian 2000 |
| Jane Mandean | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 1996, 2000, 2004 |
| Beverly Mashinini | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 2004 |
| Nathan Meyer | Para-athletics | 0 | 1 | 0 | 1 | Paralympian 2000, 2004 |
| Fabian Michaels | Para-athletics | 0 | 1 | 0 | 1 | Paralympian 2004 |
| Willem Niemann | Para-bowls | 0 | 1 | 0 | 1 | Paralympian 1996 |
| Ronald Phillips | Para-bowls | 0 | 1 | 0 | 1 | Paralympian 1996 |
| Tyrone Pillay | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 2016, 2020 |
| Elizabeth Prinsloo | Para-swimming | 0 | 0 | 1 | 1 | Paralympian 1996, 2000 |
| Samkelo Radebe | Para-athletics | 1 | 0 | 0 | 1 | Paralympian 2012 |
| Donald Ramphadi | Wheelchair tennis | 0 | 0 | 1 | 1 | Paralympian 2024 |
| Rosebella Riese | Shooting, Table tennis | 0 | 0 | 1 | 1 | Paralympian 1996, 2000, 2004 |
| Jeddie Schabort | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 1992, 1996 |
| Krige Schabort | Para-athletics | 0 | 1 | 0 | 1 | Paralympian 1992, 1996, 2004 |
| Union Sekailwe | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 2012, 2016 |
| Lucas Sithole | Wheelchair tennis | 0 | 0 | 1 | 1 | Paralympian 2024 |
| Hein Seyerling | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 2000 |
| Zivan Smith | Para-athletics | 1 | 0 | 0 | 1 | Paralympian 2012 |
| Duane Strydom | Para-athletics | 0 | 0 | 1 | 1 | Paralympian 2000, 2004 |
| Michael Thompson | Para-cycling | 0 | 0 | 1 | 1 | Paralympian 2008 |
